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OEEE
XOOX
EXEX
XEOE

Precisely one letter must be exchanged into one of many different two. However the place and which one?

I meant this to be a part of Month-to-month Matter Problem. That is type of a touch.

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I feel it is

The 2nd E within the third row, it must be an O

How come:

The entire grid appears to be like like Tic-tac-toe on a 4×4 grid. Given there are 5 Xs and 4 Os, it must be O’s flip to play. Enjoying within the 2nd empty (E) sq. within the third row ensures a win for the participant with the Os, finishing each a vertical 3 in a row and a diagonal one.
$$ start{array}{cccc} mathsf{textual content{O}} & & & mathsf{textual content{X}}& mathsf{textual content{O}} & mathsf{textual content{O}} & mathsf{textual content{X}} & mathsf{textual content{X}} & colour{lime}{mathsf{textual content{O}}} & mathsf{textual content{X}} mathsf{textual content{X}}& & mathsf{textual content{O}} & finish{array}$$

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